Concerning the reciprocal regulation of phosphofructokinase and fructose 1.6 bisphosphatase in the liver, which of the following statements are true? *
**Remember wrong answers will count against your score for this question.

A. The default activity of the cell favors activity of phosphofructokinase -2 being activated, generating fructose -2,6 -bisphosphate that serves as a potent allosteric activator of phosphofructokinase.
B. High levels of fructose -2,6- bisphosphate signals for activation of gluconeogenesis and inhibition of glycolysis
C. Glucagon binding ensures that the levels of fructose -2,6- bisphosphate drop within the liver cell
D. In the presence of ATP and fructose -2, 6- bisphosphate, phosphofructokinase will be fully inhibited and glycolysis turned off
E. Glucagon binding activates glycolysis as it signals high blood sugar levels