Terminal cisternae are discrete regions
within the muscle cell store calcium. It is an enlarged areas of the sarcoplasmic reticulum
surrounding the transverse tubules. It
also serves as the reservoirs that store the calcium required for muscle
contraction. The Calcium Release Unit Consists of Multiple Proteins on
T-tubules and Sarcoplasmic Reticulum Membranes consists of the terminal cisternae of
the sarcoplasmic reticulum and its adjacent transverse or T-tubule that is the invigilated
part of the surface membrane. The dihydropyridine
receptor (DHPR) and ryanodine
receptor (RyR), the calcium
release channel, on the sarcoplasmic reticulum are the two major proteins are
the voltage sensor on the T-tubule.